Archive Page 179

A Reluctant Interventionist

My middle-aged patient had all the risk factors for a heart attack: high blood pressure, borderline diabetes, high cholesterol, a strong family history and a sixty pack-year smoking habit.

His stress test was positive and the medications that were started in the hospital weren’t controlling his chest pains.

The cardiologist at Cityside Cardiovascular Consultants who took my call, Joe Altman, sounded tired. I have known him for over twenty-five years. He always impressed me by looking beyond just the acute problem of where a patient’s coronary blockage is and how to get rid of it.

Joe has the mindset of a generalist. He pays a great deal of attention to prevention and to each patient’s entire medical history. More than once he has contacted me to make sure I am taking care of a patient’s borderline thyroid function or some other problem most cardiologists wouldn’t concern themselves with. He has never recommended testing or interventions in a knee-jerk fashion, but always considered the patient’s entire case history. I have great respect for his conservative approach.

Joe, the senior member of his group, has seen younger cardiologists replace him in the catheterization laboratory. These days, he is often the one who takes calls from primary care doctors in the community who call with questions or urgent referrals.

“So, has he quit smoking yet?” was Joe’s first question after I finished my brief case presentation.

“He’s working on it, started bupropion today,” I answered.

“Better make sure he does… Well, I guess we’re obligated to cath him.” He paused for a moment, then sighed:

“I’ll tell’ya, I have less and less sympathy with the ones who keep smoking and come back here again and again to have us fix them up, and then go back and do the same thing all over again.”

I was taken aback a little by the emphatic frustration at the other end of the line, but not entirely surprised. Dr. Altman, probably ten years my senior and perhaps nearing retirement, must be looking back at his career. He must be thinking of all the expensive procedures that helped Cityside Cardiovascular Consultants build their magnificent new headquarters on the riverbank outside the city, yet wondering how it is that last-minute interventions seem so much more glamorous than the primary care and public health efforts to avoid and prevent heart disease in the first place.

He should have been a Family Practitioner, but I am grateful to have had him as my consultant cardiologist all these years.

A Sore Spot

Doug Leland is no stranger to back pain. After two failed back surgeries he is on long-acting narcotics in addition to high doses of seizure medications to dull the relentless nerve pain that burns day and night like an eternal fire deep inside his left leg.

A few weeks ago Doug went to the emergency room several days after slipping on his icy front steps. I read the report with some surprise. He had caught himself, and didn’t actually fall. He didn’t have broken ribs or any other serious injury, but was experiencing so much pain under his right shoulder blade that the ER doctor had decided to give him two intravenous injections of hydromorphone, a very strong, fast-acting opioid, plus high doses of a muscle relaxant and an anti-inflammatory medication.

When I saw him last week he was miserable. Every little movement of his upper body bothered him. His pain covered an area under his shoulder blade about the size of one of his large hands. Dead center in this area was an exquisitely sore spot with a palpable knot in the upper portion of his latissimus dorsi muscle. Even mild pressure on this tender spot caused a burning pain that radiated down the back of his right arm. This didn’t fit with the anatomy of any cervical or thoracic nerve.

I didn’t want to continue increasing his narcotics as they clearly weren’t providing him relief. With Doug’s ulcer history, he wasn’t a good candidate for continued anti-inflammatory drugs.

I decided to offer him something I haven’t done for a few years – a trigger point injection. They were common twenty years ago, but seem to have somewhat fallen out of fashion.

Doug was game: “Anything, Doc. Anything that might help, I’ll try it!

I mixed lidocaine and saline in a 3 cc syringe and attached a 25G 1½ inch needle. I localized the tender spot again and circled it with a ballpoint pen. I cleaned his skin with iodine and inserted the injection needle into the trigger point I had marked. I aspirated the syringe to make sure the needle wasn’t in a blood vessel.

“You’re in the right spot, Doc!” Doug groaned.

“Okay, Doug, here we go…” I told him.

A few minutes later Doug was moving his shoulders around, bending his back comfortably in all directions.

“The pain’s gone…”

“The Novocain is in the right spot, then,” I explained. “We’ll have to see if there is a lasting effect. Come back after the weekend and let me see how you’re doing.”

Doug came back, still smiling. There was a small area of tenderness several inches above where I had put the needle, but his pain was essentially gone. Doug was grateful.

“You’re a magician, Doc!”

“It’s an old trick I had almost forgotten,” I confessed.

“I’m sure glad you thought of it, Doc!”

That evening I thought more about trigger point injections. I don’t remember hearing about them in medical school or my internship in Sweden. I heard of them soon after I came to this country, thirty years ago.

I decided to do some research.

Trigger points were first described in 1942 by Janet Travell, MD. She became the personal physician to President John F Kennedy, who suffered from chronic back pain. Her first edition of “The Trigger Point Manual” was published in 1983 when I was a Family Practice resident here in the United States. I learned to inject trigger points in patients with myofascial syndrome in my residency, but this is not something all physicians learn today. Other modalities, from manual pressure to laser therapy, are now sometimes applied to trigger points.

Trigger points are thought to relate to dysfunctional end plates within the sympathetic nervous system. Acetylcholine levels and pH are thought to be important factors in myofascial pain.

The effect of trigger point injections can be reversed with naloxone, an opiate antidote. This suggests that the release of endorphins may be partly responsible for the effect of trigger point injections.

Very few articles have been published on this topic in recent years. There are few randomized controlled trials, and not all of them have found trigger point injections to be effective. One recent study found similar results for trigger point injections and acupuncture.

There are many similarities between trigger points and acupuncture points, but they have been viewed as very different in how they work. Trigger point injections, regardless of which chemical is used, are thought to cause physical changes at the injection site. Some clinicians even do “dry needling” of trigger points with the same results. The insertion of an acupuncture needle is generally thought to affect energy flow in predetermined meridians.

Intentional or accidental trigger point pressure can cause referred pain in other locations, similar to the correlation between acupuncture points and meridians. In fact, a 2006 study shows that of 255 trigger points with referred pain patterns described by Janet Travell and her collaborator, David Simons, 170 correspond to classic and 64 to newer acupuncture points and their meridians. This raises the question of whether the 70-year-old trigger point theory isn’t just Western medicine’s rediscovery of an ancient form of energy medicine. Doug’s pain pattern, radiating from the tip of she shoulder blade to the back of the arm, fits one described by Travell. It also closely follows one of the large acupuncture meridians.

What I did in the case of Doug Leland the other day may not just date back to 1942, but three or four thousand years.

The Art of Scheduling: Air Traffic Control in the Medical Office

Our clinic has an advanced computer scheduling system. It gives overviews of available appointments, makes statistical reports and shows several providers’ schedules in one view. But it can’t even begin to compare with Doreen and her paper and pencil system.

Doreen was our master scheduler more than ten years ago. She moved on to become the office manager in a specialist’s office, but then got tired of modern medicine and opened a country store.

Without any formal medical training, Doreen instinctively knew who needed to be squeezed into their provider’s schedule urgently and who could wait, and how long each type of visit would take for each of our differently tempered medical providers. At the same time she was able to keep track of the future appointments each patient had without the benefit of a computer.

Doreen knew our patients well enough to know who needed an extra long appointment no matter what ailed them. She also knew which patients were straightforward enough to be squeezed in for acute illnesses. She knew that “double books” really weren’t physically possible as no doctor is good enough or fast enough to be in two exam rooms with two different patients at the same time. She was able to look at her paper and pencil schedule and see that Mrs. Smith’s blood pressure check on Tuesday morning was just a quick visit to check her blood pressure, review her potassium level and write one or two prescriptions whereas Mrs. Brown’s blood pressure visit Tuesday afternoon was likely to be an outdrawn affair because of her husband’s dementia and her daughter’s recent breast cancer diagnosis. A child with an earache could have five minutes of Mrs. Smith’s 15 minutes, but nobody could be squeezed into Mrs. Brown’s timeslot.

With the precision of an air traffic controller, Doreen would schedule the straightforward Mrs. Smith’s blood pressure visit for 10:00, little Danny Swan’s earache for 10:10 and the next regular visit at 10:15. When Doreen scheduled, everything ran on time, just like a Swiss train.

She once told me: “If I can’t tell on the phone what sort of problem they’re having, not even you can figure it out and take care of it in a double booked 5-minute visit, but if they know what they need, I’ll squeeze them in”.

Doreen constantly scanned the wide lined double page spread of her appointment book and kept an eye out for potential office bottlenecks. She would make sure several providers weren’t doing pap smears at the same time, since too many nurses would then be tied up and not available for telephone triage. She watched out for room or equipment conflicts – two cryosurgeries at the same time and needing the same equipment never happened while Doreen was in charge. Our fancy computer schedule can be used to schedule the procedure room, but doesn’t spot for the little conflicts Doreen was always on the lookout for.

Doreen effortlessly and intuitively mixed fast and slow visits throughout the day, so that two patients with the potential for running over were never scheduled back to back. If a visit ran over a little, chances were good that the next visit would allow me to catch up. Thanks to her wisdom, I seldom felt rushed, even though I regularly saw record numbers of patients during her reign at the front desk.

No amount of color-coding or drop-down menus could match Doreen and her old-fashioned system. Her compassionate dedication and the simple flexibility of her paper and pencil appointment book kept our clinic humming.

Intuiting Alexithymia

“Tell me about the day you passed out,” I asked the middle-aged woman in Room 4 the other morning. “How did you feel?”

“We were up early, my husband and I, because Debbie – that’s our daughter – was coming home for Easter break. She’s on the dean’s list at Swartham College. She wants to be a civil engineer with a double in business administration. She’s so talented…”

“Were you feeling okay when you woke up?” I tried to redirect her.

“Well, Gordon looked at me kind of funny and asked if I was feeling all right…”

“Were you?”

“He didn’t think I looked well. Pasty, he said my face was… Pasty-looking!” She sighed. “I didn’t finish my toast or my bran flakes, and I usually gulp my breakfast before Gordon even gets back in the house with the morning paper.”

“Did you feel nauseous?”

“I didn’t throw up, if that’s what you mean. Gordon asked me the same thing. He felt my forehead and said I was clammy.”

“Then, what happened?”

“We got ready to go to the airport to pick Debbie up. On the way, I asked Gordon to stop at Dunkin’ Donuts and get me some Munchkins, but he was worried we’d be too late, so he talked me out of it.”

I started to be increasingly aware of the time.

“Do you remember the moments before you passed out? What did you feel?” I asked.

“I remember thinking it was hot in the luggage hall, and I remember Debbie talking about her new roommate. Then Gordon said he should have stopped for Munchkins after all, because we had had plenty of time and I was probably getting a low blood sugar…”

I changed my strategy and asked several more directed, yes-or-no questions. I formulated a plan for what kind of workup to do.

The rest of the day I kept thinking about that encounter. Over the years I have seen so many patients who don’t seem to be able to describe or even recognize their own feelings, but instead tell me what other people notice about how they appear to them. I have often wondered if there was a name and a psychological profile for people like that. They are a challenge to take a medical history from, but they must also be challenged themselves by never really knowing how or what they feel.

Last night after supper, my brother-in-law called from the west coast. While my wife talked with him, I Googled my question.

“Inability to describe own feelings, relying on other people’s description” I typed.

The third link on my search gave me the word I needed: “What is alexithymia?” The literal meaning of a-lexi-thymia is “lack of words (for) emotion”. I searched for “alexithymia” and a half-dozen articles completely captured my attention while my wife and her brother continued their telephone conversation.

What I read resonated with my own observations. Curiously, the first website I looked at had been posted or updated the day before my search and the original article by P.E. Sifneos, introducing the word and describing the phenomenon, was published in 1973 – the year before I started medical school. It took me this long to “discover” it myself!

Alexithymia is not classified as a disease in DSM-IV, the psychiatric book of diagnostic definitions. It is rather more like a personality type. What I found fascinating as I read along is the link between alexithymia and psychosomatic illness.

People with alexithymia can’t tell if their bodily sensations represent physical or emotional phenomena, because they have trouble registering their emotions. They are likely to look for physical illness as an explanation for sensations others may easily recognize as related to strong emotions. An extreme example from one of the websites I read was that a crying alexithymic might worry about having a blocked tear duct instead of registering their sadness. A person with little insight into how upset, sad or anxious he or she might be would not have any ability to judge whether they might feel bad, be it headache, chest pain or belly cramps, for emotional reasons.

One article suggested up to 10% of people have some degree of alexithymia.

Those impromptu few minutes on the computer made me a wiser clinician. I will be more tenderhearted with patients who have trouble describing their feelings in a fifteen-minute visit, and I will look harder for that trait in patients whose symptoms baffle me.

Clinical Instinct

“The young man knows the rules, but the old man knows the exceptions.”

Oliver Wendell Holmes, Sr., M.D.

I have been reading from two e-books lately on my new iPad. One of them, a bestseller published in 2005, is “Blink”, subtitled “The Power of Thinking Without Thinking” by Malcolm Gladwell. The other book, digitized by the Gutenberg project and first published in the late 1800’s, is “Medical Essays 1842-1882” by Oliver Wendell Holmes, Sr., physician, Harvard dean, poet and friend of Emerson and Longfellow.

As I read along I realized the two works both happened to address what clinical instinct really is, compared with pure book-knowledge, a question that is more important now than in recent memory as we strive to digitize and standardize every aspect of the practice of medicine.

In our decade, Gladwell, a British-born, Canadian-raised writer for “The New Yorker”, writes about the value of our subconscious calculations, which are faster and more accurate than our conscious, logic-based, conclusions. This applies also in medicine. Gladwell writes on his website (http://www.gladwell.com/blink/):

“One of the stories I tell in “Blink” is about the Emergency Room doctors at Cook County Hospital in Chicago. That’s the big public hospital in Chicago, and a few years ago they changed the way they diagnosed heart attacks. They instructed their doctors to gather less information on their patients: they encouraged them to zero in on just a few critical pieces of information about patients suffering from chest pain–like blood pressure and the ECG–while ignoring everything else, like the patient’s age and weight and medical history. And what happened? Cook County is now one of the best places in the United States at diagnosing chest pain.”

In “Blink”, Gladwell describes how professional gamblers start avoiding cards from a stacked deck as their biometric parameters, like skin temperature, register stress, long before they consciously become aware of what is occurring.

150 years earlier, in the essay “The Young Practitioner”, Holmes wrote about clinical instinct in the experienced physician:

“Book-knowledge, lecture-knowledge, examination-knowledge, are all in the brain. But work-knowledge is not only in the brain, it is in the senses, in the muscles, in the ganglia of the sympathetic nerves,—all over the man, as one may say, as instinct seems diffused through every part of those lower animals that have no such distinct organ as a brain. See a skilful surgeon handle a broken limb; see a wise old physician smile away a case that looks to a novice as if the sexton would soon be sent for; mark what a large experience has done for those who were fitted to profit by it, and you will feel convinced that, much as you know, something is still left for you to learn.

The young man knows the rules, but the old man knows the exceptions. The young man knows his patient, but the old man knows also his patient’s family, dead and alive, up and down for generations. He can tell beforehand what diseases their unborn children will be subject to, what they will die of if they live long enough….The young man feels uneasy if he is not continually doing something to stir up his patient’s internal arrangements. The old man takes things more quietly, and is much more willing to let well enough alone: All these superiorities, if such they are, you must wait for time to bring you.”

I have seen many examples of situations when you simply can’t get caught up in all the details of history taking and physical exam. Clinical observation, where all the physician’s senses become involved, can be faster and safer. Our whole reimbursement system, however, rewards doctors for asking lots of questions and evaluating as many (even irrelevant) body systems as possible, not for quickly and efficiently making the correct diagnosis.

Early in my career, I was asked to evaluate an elderly woman with shoulder pain. It was of recent onset and without any trauma, and it hurt her to move her arm. I ignored the sweat on her brow and her rapid pulse and high blood pressure and sent her home with instructions for caring for tendinitis of the shoulder. Not long after, an older colleague admitted her to the hospital for a myocardial infarction. My instincts were correct, but my orthopedic exam mislead me.

I vividly remember one day, many years ago, when my wife who is a nurse practitioner called me in to see a young child she was evaluating.

“He just doesn’t look right,” she said.

His vital signs were normal, and his history was benign, but I got the same uneasy feeling.

Moments later, his eyes rolled back, his muscle tone vanished, and he stopped breathing. By that time I already had my arms around his little body and was soon doing infant CPR. My wife and I both knew the child wasn’t right, but neither one of us have been able to describe how we knew.

Would today’s, or tomorrow’s, medical software or artificial intelligence have been able to discern that our young patient was about to slip out of consciousness and why? And if not, how do we ensure that the human beings who practice the art of medicine are allowed and encouraged to cultivate their clinical judgment in this era of standardized and managed care?


I just realized none of the posts show on an iPad or a computer, but they do show on an iPhone. WordPress is working on this. In the meantime, please visit my Substack.

 

 

Osler said “Listen to your patient, he is telling you the diagnosis”. Duvefelt says “Listen to your patient, he is telling you what kind of doctor he needs you to be”.

 

BOOKS BY HANS DUVEFELT, MD

CONDITIONS, Chapter 1: An Old, New Diagnosis

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