Archive Page 13

Reverse White Coat Hypertension in a Patient with Anxiety: Treat the Blood Pressure or Treat the Anxiety?

The other day, I saw a woman who was interviewing me in order to decide whether to transfer her care to my practice. That happens now and then.This woman had the diagnoses of hypertension and of general anxiety, as well as a few other things that I didn’t think immediately related to the reason she was considering finding another doctor.

In some office visits with her various specialists and primary care doctor her blood pressure was as low as 118 but most of the time in the mid 120s and occasionally it hit 145. At home, she ranged from 140 to 200.

This is what we call reverse white coat hypertension. This woman had essentially normal readings in the office and almost always ran high at home. It is much less common than white coat hypertension where the medical office environment triggers an adrenaline rush that raises a patient’s blood pressure sometimes.

Her primary care doctor had tried her on many different blood pressure pills without much luck. Her psychiatrist had her on the maximum dose of venlafaxine plus a few other things. In addition to that, she is prescribed 14 tablets of clonazepam with instructions that it has to last her a whole month and not to call for an early refill.

Clonazepam is a benzodiazepine just like Valium or Xanax. The only real difference between the benzodiazepines is how fast they kick in and how long they stay in your system. For people who take them for anxiety in certain situations, Xanax is often used. It is viewed as more addictive because patients feel the relief when it starts to work and experience dread a few hours later when it starts to wear off. Most prescribers think it is good only for rare situations like when flying in an airplane or going to the dentist. Clonazepam on the other hand is slow to kick in and slow to wear off and most of us use it only for chronic anxiety when the usual preventative medication aren’t working. It is dosed once every 12 to 24 hours, so it seemed odd to me that an experienced psychiatrist would dole out 14 tablets a month to be used as needed for somebody with anxiety every single day.

She lives in a housing development where she hears her neighbors through the walls. She sleeps on the living room couch, where she can see the front door, and never uses her bed or even her bedroom for that matter. She worries about people breaking in and sometimes she doesn’t even know exactly what is making her feel anxious. She doesn’t know where she might feel safer or happier, so she feels stuck and paralyzed without even any vision of how or where her life could be better. She completely rejected my suggestion of considering a roommate, maybe even in a different place, living a little bit like in the old sitcom “Golden Girls”.

I know exactly what is going on here. They teach you in medical school that if you try several blood pressure medications without success, it is time to look for what’s driving this. It could be hormonal problem with the thyroid or the adrenal glands. It could be too much alcohol, narrowing of the kidney arteries and many other things. Or it could be stress and anxiety. In this case, it seemed obvious that the anxiety is the driver because this woman, who spends every day and every night alone, has better blood pressures when she is in the presence of another human being.

I know exactly what is going on here in another way. Doctors who work for big hospital systems are often bound by policies and guidelines or simply an unwritten bias within their organizations. Benzodiazepines are like opiates in the sense that they are potentially addictive drugs that may be appropriate for short-term use, but they both have a phenomenon called tachyphylaxis. What that means is that people often develop a tolerance to the medication and over time need more and more for the same effect that they had when they first seemed to benefit from it. For this reason, hospitals, group practices, medical boards and various watchdog are working hard to minimize unnecessary use of these drugs.

This patient’s primary care provider is part of the same big organization so they would also be under pressure to avoid continuous prescribing of benzodiazepines.

So what I did was tell this anxious woman to really talk seriously with her psychiatrist in her upcoming visit about how the venlafaxine is not preventing the anxiety, she feels stuck where she is in an environment where she doesn’t feel safe and the clonazepam gives her good relief on the days she takes it, but if she cannot have it every day, she needs her psychiatrist’s help in getting something else that reduces her anxiety. There are many options for this, but taking a long acting drug only some days and not at all on other days doesn’t sound like a good long-term solution to me.

In some ways, prescribing the long acting clonazepam to be taken when she feels like she needs it the most, essentially, would be like taking a blood pressure pill on days where she thinks her blood pressure might be going extra high. We hardly ever do that, so what’s different in this case?

Personas in the Practice of Medicine

Skimming through posts by other writers on Substack, I came across a short piece that started a chain reaction in my brain. Its title was Who did I meet in my clinic?

The author described the diseases in his patient encounters as personas who had more or less invaded the lives of the people afflicted by them. Suddenly that made a lot of sense to me, and I saw all the parallels to how we use the concept and the word personas or sometimes personalities for not just our patients, but medications and diseases and also, from a psychological perspective, archetypal individuals who shaped the life of our patients and, really, all of us.

I had never myself quite claimed the insight that diseases have personalities, but they do. Some diseases are always slow, some always fast and dramatic, some wax and wane and can sneak back up on you even when you think you are cured. Some follow a course of tightly scripted stages. Seasoned clinicians are intuitive masters of pattern recognition, which really means recognizing the personalities of diseases.

I often speak and write about how medications have personalities. Prozac can be energizing, Paxil can insulate you from emotional pain, Wellbutrin can make you less angry, Remeron can make you hungry, steroids can de-stabilize your mood and so on.

In all types of sales and marketing, the term persona can be used for training purposes in describing customers with varying degrees of interest or ability to buy a product. Are they just looking, do they want lots of information or will they make an emotional decision?

As a doctor meeting a new patient, I need to read them and try to figure out what they are looking for and I need to behave in a way that I believe is effective in building rapport and trust and a therapeutic relationship. I try to assess the patient’s personality or persona, and I show more of certain aspects of my own personality as the situation might require. Some people think this is dishonest, I feel very strongly that it is necessary if you want to reach people and help them heal.

Another important application of the concept of personas is those individuals who shaped our lives, archetypes in Jungian terminology. Being raised by a narcissistic mother is just one example of common personality types ability to influence others.

All this reminded me of the title of an Ingmar Bergman film, Persona, which I never watched as a young man in Sweden. The trailer on YouTube was not appetizing, so I don’t know that I will take the plunge and watch the movie, but it is supposed to have lot of Jungian stuff in it.

The bottom line here is that everything has personalities, breeds of dogs, brands of cars, types of wood, digital recordings, vinyl, albums, printed books and e-books.

It’s just a useful analogy in most walks of life.

Curbside Consults by Subscription

(As I hit PUBLISH for this post, I got a notice from WordPress that this was my thousandth blog post on ACDW!)

When I started out, most specialists were in private practice, as were most primary care doctors. Fresh out of my residency, the specialist consultants I referred to were obviously a little older than I. They were well established, made good money and were their own bosses. The grace in their lives was obvious to me.

Their consultation reports were typed on delicious, thick, often colored, stationery and signed with flair, often with a fountain pen. If I called them for what we call “curbside” advice, they were gracious and never seemed rushed. They took pleasure in sharing their knowledge with younger colleagues like me. I’m sure they also expected our referrals over time to be better and more appropriate.

Times have changed. Most of the specialty practices were bought up by the hospitals and specialist doctors became employees with a little less control over how their day went. I could tell when I called for advice that they had tighter schedules than they used to. Many of them also had less help in the office than they were used to having.

The other thing that happened over time was that, since they were all older than I was when I began practicing, one by one, most of them have now retired. The new generation of specialist isn’t as easy for me to call for curbside consultations because we don’t have as much history with each other.

My new practice has a subscription to a nationwide service that I was late in starting to utilize, but now I am hooked. I go to the service’s website, type my question and the clinical background, import labs or imaging reports and, typically in half an hour or less, get a helpful reply from a specialist with at least comparable credentials to what I was used to years ago, and often from somebody with an academic background.

I have received no-nonsense, real-world guidance with a urine culture growing enterococcus faecalis, with a case of Todd paralysis and once got ammunition in the case of an elderly cholecystitis patient with a cholecystotomy tube my local surgeons didn’t want to deal with.

I am now telling my patients here in this physician shortage area that I have almost instant access to specialists and subspecialists my patients would have to wait many months and travel hundreds of miles to see. This sometimes lets me handle more things myself and at the very least it helps ensure that my patients will get the right treatment while they wait for their “local” consultation here in Maine.

My practice actively encourages its doctors and nurse practitioners to use this service. This is such a time saver and worry reducer for both us frontline clinicians and for our patients.

A Country Doctor Writes -Again!

Between first being too busy and then catching something protracted that has felt just like Covid, I have finally regained enough energy for some future posts, still in title only or first paragraph only format – I don’t draft and edit. I put down a start and if I don’t finish it right away, I do it later in one fell swoop.

Here is my recent Facebook post:

Recovering slowly from a virus that drained all my batteries, I remembered a favorite poem from my youth: FEVER, by John Updike.

I have just brought back a good message from the land of 200 (degrees):
God exists.
I had severely doubted it before:
but the bedposts spoke of it with utmost confidence,
the threads in my blanket took it for granted,
the tree outside the window dismissed all complaints,
and I have not slept so justly for years.
It is hard now to convey
how emblematically appearances sat
upon the membranes of my consciousness;
but it is a truth long known
that some secrets are hidden from health.

What’s in a Number? Why All These Binary Definitions of Health and Disease?

A blood pressure of 139/89 would be considered okay, but a reading of 140/90 on the last visit of the year gives the treating physician a failing grade, also called a “Care Gap” in the category of Controlling Blood Pressure. Never mind if that last appointment happened while the patient had a broken rib and was in pain. The same binary standard applies to hemoglobin A1c as to whether diabetes is controlled or not co The same binary standard applies to hemoglobin A1c as to whether diabetes is controlled or not compare that with the Fed, changing interest rates by a quarter of a point every so many months and making big news in the proces. Compare that with the Fed, changing interest rates by a quarter of a point every so many months and making big news in the process.

The practice of medicine is getting sillier and sillier the more we are held to “quality” measures. That is a substitute marker for outcomes. If you think about it, I could start a heavy duty blood pressure medication on my patient with a broken rib and reactive blood pressure from that and bring him back for a recheck before the end of the year and thus meet my quality parameters. In early January, when the rib fracture is no longer causing pain, the patient has an orthostatic blood pressure drop, falls to the ground, landing on cement and dies from a subdural hematoma. I would still be in good shape with my quality metrics.

The modern risk calculators that we use to assess cardiovascular risk in people with elevated cholesterol make it very plain that cardiovascular risk is a multifactorial calculation. Why we don’t have a similar view of blood pressure when we could use the cholesterol risk calculators to illustrate the difference between two different blood pressure numbers, whether with or without medication is, simply, ignorant.

In medicine today, not even gender is considered a binary metric. Why in the world are we then viewing cholesterol, blood pressure, or even blood sugar for that matter, more clearly defined than gender? If medical providers are too lazy to plug in blood pressure numbers into the cardiac risk calculators to determine the value of treating such blood pressures, perhaps AI can be of help doing the math for us?


I just realized none of the posts show on an iPad or a computer, but they do show on an iPhone. WordPress is working on this. In the meantime, please visit my Substack.

 

 

Osler said “Listen to your patient, he is telling you the diagnosis”. Duvefelt says “Listen to your patient, he is telling you what kind of doctor he needs you to be”.

 

BOOKS BY HANS DUVEFELT, MD

CONDITIONS, Chapter 1: An Old, New Diagnosis

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